Staff
Etsu TashiroAssociate Professor / Ph.D.last update : 2022.11.15
Japanese
Profile
- Name
- Etsu Tashiro
- Affiliation
- Laboratory of Biochemistry
- Subjects
- Biochemistry I
Biochemistry II
- Official title
- Associate Professor
- Degree
- Ph.D.
- Bioprobe 2nd edition “Biochemical Tools for Investigating Cell Function” Tashiro E, Kitagawa M and Imoto M Chapter 4 75-114 Springer 2017
- Control of Cellular Physiology by E2F Transcription Factors Minato Y, Tashiro E, Kanai M and Imoto M 153-165 2008
- [Original paper] Ktedonoketone and 2'-oxosattabacin, benzenoid metabolites from a thermophilic bacterium?Thermosporothrix hazakensis?in the phylum?Chloroflexi Igarashi Y, Yamamoto K, Ueno C, Yamada N, Saito K, Takahashi K, Enomoto M, Kuwahara S, Oikawa T, Tashiro E, Imoto M, Xiaohnyao Y, Zhou T, Harunari E, Oku?N. J Antibiot (Tokoyo) 72 653 2019
- [Review] Screening and identification of inhibitors of endoplasmic reticulum stress-induced activation of the IRE1α-XBP1 branch Tashiro E J Antibiot (Tokoyo) 72 899 2019
- [Original paper] 14-3-3εa directs the pulsatile transport of basal factors towards the apical domain for lumen growth in tubulogenesis Mizotani Y, Suzuki M, Hotta K, Watanabe H, Shiba K, Inaba K, Tashiro E, Oka K, Imoto M. PNAS 115 E8873 2018
- [Original paper] Metacycloprodigiosin induced cell death selectively in β-catenin-mutated tumor cells Ikeda H, Shikata Y, Watanapokasin R, Tashiro E, Imoto M J Antibiot (Tokoyo) 70 109 2017
- [Original paper] Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin-containing protein inhibitor Shikata Y, Yoshimaru T, Komatsu M, Katoh H, Sato R, Kanagaki S, Okazaki Y, Toyokuni S, Tashiro E, Ishikawa S, Katagiri T, Imoto M Cancer Sci 108 785 2017
- [Original paper] Nonthmicin, a Polyether Polyketide Bearing a Halogen-Modified Tetronate with Neuroprotective and Antiinvasive Activity from Actinomadura sp. Igarashi Y, Natsuoka N, In Y, Kataura T, Tashiro E, Saiki I, Sudoh Y, Duangmal K, Thamchaipenet A Org Lett 19 1406 2017
- [Review] Chemistry and biology of the compounds that modulate cell migration Tashiro E and Imoto M J Ind Microbiol Biotechnol 43 213 2016
- [Original paper] Involvement of the MEK/ERK pathway in EGF-induced E-cadherin down-regulation Tashiro E, Henmi S, Odake H, Ino S, Imoto M Biochem Biophys Res Commun 477 801 2016
- [Original paper] SMK-17, a MEK1/2-specific inhibitor, selectively induces apoptosis in β-catenin-mutated tumors Kiga M, Nakayama A, Shikata Y, Sasazawa Y, Murakami R, Nakanishi T, Tashiro E, and Imoto M Sci Rep 5 8155 2015
- [Original paper] Apoptosis induction associated with the ER stress response through up-regulation of JNK in HeLa cells by gambogic acid Krajamg A, Imoto M, Tashiro E, Fujimaki T, Shinjo S, and Watanapokasin R BMC Complement Altem Med 15 26 2015
- [Original paper] Evaluation of drug toxicity profiles based on the phenotypes of ascidian Ciona intestinalis Mizotani Y, Itoh S, Hotta K, Tashiro E, Oka K, and Imoto M Biochem Biophys Res Commun 463 656 2015
- [Review] Chemical biology of compounds obtained from screening using disease models Tashiro E and Imoto M Arch Pharm Res 38 1651 2015
- [Original paper] 5-lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor-induced cell migration through Tiam1 upregulation and Rac1 activation Magi S, Takemoto Y, Kobayashi H, Kasamatsu M, Akita T, Tanaka A, Takano K, Tashiro E, Igarashi Y, and Imoto M Cancer Sci 105 290 2014
- [Original paper] Chemical genomic-based pathway analyses for epidermal growth factor-mediated signaling in migrating cancer cells Magi S, Saeki Y, Kasamatsu M, Tashiro E, and Imoto M PLoS One 9 e96776 2014
- [Original paper] Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson’s disease Fujimaki T, Saiki S, Tashiro E, Yamada D, Kitagawa M, Hattori N, and Imoto M PLoS One 9 e100395 2014
- [Original paper] Xanthohumol suppresses oestrogen-signaling in breast cancer through the inhibition of BIG3-PHB2 interactions Yoshimaru T, Komatsu M, Tashiro E, Imoto M, Osada H, Miyoshi Y, Honda J, Sasa M, and Katagiri T Sci Rep 4 7355 2014
- [Original paper] Boronic Acid Inhibitors of Acyl Protein Thioesterase 1 and 2 Zimmermann TJ, Burger M, Tashiro E, Kondoh Y, Martinez NE, Gormer K, Rosin-Steiner S, Shimizu T, Ozaki S, Mikoshiba K, Watanabe N, Hall D, Vetter IR, Osada H, Hedberg C and Waldmann H Chembiochem 14 115 2013
- [Original paper] Novel derivatives of aclacinomycin A block cancer cell migration through inhibition of farnesyl transferase Magi S, Shitara T, Takemoto Y, Sawada M, Kitagawa M, Tashiro E, Takahashi Y and Imoto M J Antibiot (Tokoyo) 66 165 2013
- [Original paper] Comparative Analysis of the UPR-Target Genes Expression Patterns induced by UPR-Inducing Compounds Shinjo S, Mizotani Y, Tashiro E and Imoto M Biosci Biotechnol Biochem 77 729 2013
- [Original paper] Establishment of a new detection system for the dimerization of IRE1α using a BiFC assay Shinjo S, Tashiro E and Imoto M Biosci Biotechnol Biochem 77 1333 2013
- [Original paper] Antitumor effects of novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor, SMK-17 Kiga M, Tanzawa F, Iwasaki S, Inaba F, Fujiwara K, Iwadare H, Echigo T, Nakamura Y, Shibata T, Suzuki K, Yasumatsu I, Nakayama A, Sasazawa Y, Tashiro E, Imoto M and Kurakata S Anticancer Drugs 23 119 2012
- [Review] Target identification of bioactive compounds Tashiro E and Imoto M Bioorg Med Chem 20 1910 2012
- [Original paper] Napyradiomycin A1, an inhibitor of mitochondrial complex I and II Yamamoto K, Tashiro E, Motohashi K, Seto H and Imoto M J Antibiot (Tokoyo) 65 211 2012
- [Original paper] Xanthohumol impairs autophagosome maturation through direct inhibition of valosin-containing protein Sasazawa Y, Kanagaki S, Tashiro E, Nogawa T, Muroi M, Kondoh Y, Osada H and Imoto M ACS Chem Biol 7 892 2012
- [Original paper] Inostamycin enhanced TRAIL-induced apoptosis through DR5 up-regulation on the cell surface Yamamoto K, Makino M, Watanapokasin R, Tashiro E and Imoto M J Antibiot (Tokoyo) 65 295 2012
- [Original paper] Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a Potent Inhibitor of ER stress-induced XBP1 mRNA Splicing Ri M*, Tashiro E*, Oikawa D, Shinjo S, Tokuda M. Yokouchi Y, Narita T, Masaki A, Ito A, Ding J, Kusumoto S, Ishida T, Komatsu H, Shiotsu Y, Ueda R, Iwawaki T, Imoto M and Iida S Blood Cancer J 2 e79 2012
- [Original paper] A chemical genetic study identifying diversity in cell migration signaling in cancer cells Magi S, Tashiro E and Imoto M Sci Rep 2 823 2012
- [Original paper] Synthesis and anti-migrative evaluation of moverastin derivatives Sawada M, Kubo S, Matsumura K, Takemoto Y, Kobayashi H, Tashiro E, Kitahara T, Watanabe H and Imoto M Bioorg Med Chem Lett 21 1385 2011
- [Original paper] A new, convenient cell-based screening method for small-molecule glycolytic inhibitors Kitagawa M, Misawa M, Ogawa S, Tashiro E and Imoto M Biosci Biotechnol Biochem 75 367 2011
- [Original paper] Quinotrierixin inhibited ER stress-induced XBP1 mRNA splicing through inhibition of protein synthesis Yamamoto K, Tashiro E and Imoto M Biosci Biotechnol Biochem 75 284 2011
- [Original paper] Mycotrienin II, a translation inhibitor that prevents ICAM-1 expression induced by pro-inflammatory cytokines Yamada Y, Tashiro E, Taketani S, Imoto M and Kataoka T J Antibiot (Tokoyo) 64 361 2011
- [Original paper] Generation of ‘Unnatural Natural Product’ library and identification of a small molecule inhibitor of XIAP Kawamura T, Matsubara K, Otaka H, Tashiro E, Shindo K, Yanagita RC, Irie K and Imoto M Bioorg Med Chem 19 4377 2011
- [Original paper] Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration Kobayashi H, Ogura Y, Sawada M, Nakayama R, Takano K, Minato Y, Takemoto Y, Tashiro E, Watanabe H and Imoto M J Biol Chem 286 39259 2011
- [Original paper] Isolation and structure elucidation of a novel androgen antagonist, arabilin, produced by Streptomyces sp. MK756-CF1 Kawamura T, Fujimaki T, Hamanaka N, Torii K, Kobayashi H, Takahashi Y, Igarashi M, Kinoshita N, Nishimura Y, Tashiro E and Imoto M J Antibiot (Tokoyo) 63 601 2010
- [Original paper] Metabolomic identification of the target of the filopodia protrusion inhibitor glucopiericidin A Kitagawa M, Ikeda S, Tashiro E, Soga T and Imoto M Chem Biol 17 989 2010
- [Original paper] Transcriptional regulation of human fibroblast growth factor receptor 1 by E2F-1 Kanai M, Tashiro E, Maruki H, Minato Y and Imoto M Gene 438 49 2009
- [Original paper] V-ATPase Inhibitors Overcome Bcl-xL-mediated Chemoresistance through Restoration of a Caspase-independent Apoptotic Pathway Sasazawa Y, Futamura Y, Tashiro E and Imoto M Cancer Sci 100 1460 2009
- [Original paper] Oligomycin induced the proteasomal degradation of cyclin D1 Kanai M, Iba S, Okada R, Tashiro E and Imoto M J Antibiot (Tokoyo) 62 425 2009
- [Original paper] Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bcl-xL from Microbial Origin Futamura Y, Sawa R, Umezawa Y, Igarashi M, Nakamura H, Hasegawa K, Yamasaki M, Tashiro E, Takahashi Y, Akamatsu Y and Imoto M J Am Chem Soc 130 1822 2008
- [Original paper] Identification and characterization of mouse type II platelet-derived growth factor receptor a transcript Minato Y*, Nihei Y*, Kodama Y, Tashiro E, Kanai M and Imoto M Biosci Biotechnol Biochem 72 759 2008
- [Original paper] SAR study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation. I. Taxonomy, Fermentation, Isolation, and Biological activities and SAR study Kawamura T, Tashiro E, Yamamoto K, Shindo K and Imoto M J Antibiot (Tokoyo) 61 303 2008
- [Original paper] SAR study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation. II. Structure Elucidation Kawamura T, Tashiro E, Shindo K and Imoto M J Antibiot (Tokoyo) 61 312 2008
- [Original paper] Involvement of PP2A nuclear accumulation and subsequent inactivation of AP-1 in leptomycin B-inhibited cyclin D1 expression Tsuchiya A, Tashiro E, Yoshida M and Imoto M Oncogene 26 1522 2007
- [Review] Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression Tashiro E, Tsuchiya A and Imoto M Cancer Sci 98 629 2007
- [Original paper] Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA Kaida D, Motoyoshi H, Tashiro E, Nojima T, Hagiwara M, Ishigami K, Watanabe H, Kitahara T, Yoshida T, Nakajima H, Tani T, Horinouchi S and Yoshida M Nat Chem Biol 3 576 2007
- [Original paper] Transcriptional regulation of a new transcript variant of human platelet-derived growth factor receptor α by E2F-1 Minato Y, Tashiro E, Kanai M, Nihei Y, Kodama Y and Imoto M Gene 403 89 2007
- [Original paper] Trierixin, a Novel Inhibitor of ER Stress-induced XBP1 Activation from Streptomyces sp. I. Taxonomy, Fermentation, Isolation, and Biological activities Tashiro E, Hironiwa N, Kitagawa M, Futamura Y, Suzuki S, Nishio M and Imoto M J Antibiot (Tokoyo) 60 547 2007
- [Original paper] Trierixin, a Novel Inhibitor of ER Stress-induced XBP1 Activation from Streptomyces sp. II. Structure Elucidation Futamura Y, Tashiro E, Hironiwa N, Kohno J, Nishio M, Shindo K and Imoto M J Antibiot (Tokoyo) 60 582 2007
- [Original paper] Suppression of multidrug resistance by migrastatin Takemoto Y, Tashiro E and Imoto M J Antibiot (Tokoyo) 59 435 2006
- [Original paper] GSK-3beta directly phosphorylates and activates MARK2/PAR-1 Kosuga S*, Tashiro E*, Kajioka T, Ueki M, Shimizu Y and Imoto M J Biol Chem 280 42715 2005
- [Original paper] Chemistry and biology of moverastins, inhibitors of cancer cell migration, produced by Aspergillus Takemoto Y, Watanabe H, Uchida K, Matsumura K, Nakae K, Tashiro E, Shindo K, Kitahara T and Imoto M Chem Biol 12 1337 2005
- [Original paper] Involvement of nuclear accumulation of heat shock protein 27 in leptomycin B-induced apoptosis in HeLa cells Tsuchiya A, Tashiro E, Yoshida M and Imoto M J Antibiot (Tokoyo) 58 810 2005
- [Original paper] Overexpression of cyclin D1 contributes to malignancy by up-regulation of FGF receptor 1 via the pRB/E2F pathway Tashiro E, Maruki H, Minato Y, Doki Y, Weinstein IB and Imoto M Cancer Res 63 424 2003
- [Original paper] Regulation of FGF receptor-2 expression by transcription factor E2F-1 Tashiro E, Minato Y, Maruki H, Asagiri M and Imoto M Oncogene 22 5630 2003
- [Original paper] Herbimycin A induces G1 arrest through accumulation of p27Kip1 in cyclin D1-overexpressing fibroblasts Endo N, Tashiro E, Umezawa K, Kawada M, Uehara Y, Doki Y, Wesinstein IB and Imoto M Biochem Biophys Res Commun 267 54 2000
- [Original paper] Inhibition of cyclin D1 expression and induction of apoptosis by Inostamycin in small cell lung carcinoma cells Imoto M, Tanabe K, Simizu S, Tashiro E, Takada M and Umezawa K Jpn J Cancer Res 89 315 1998
- [Original paper] Caspase-3 activation is not responsible for Vinblastine-induced Bcl-2 phosphorylation and G2/M arrest in small cell lung carcinoma Ms-1 cells Tashiro E, Simizu S, Takada M, Umezawa K and Imoto M Jpn J Cancer Res 89 940 1998
- [Original paper] Potentiation of Paclitaxel cytotoxicity by Inostamycin in human small cell lung carcinoma, Ms-1 cells Simizu S, Tanabe K, Tashiro E, Takada M, Umezawa K and Imoto M Jpn J Cancer Res 89 970 1998
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