??.z%R ?0?0?0?0 W?? ?? T ?]?S ?0?0?0 ?QHrt^ DOI URL ?SW???e "Bivalent HIV-1 Fusion Inhibitors Based on Peptidomimetics." "Takuya Kobayakawa, Kento Ebihara, Kohei Tsuji, Takuma Kawada, Masayuki Fujino, Yuzuna Honda, Nami Ohashi, Tsutomu Murakami & Hirokazu Tamamura*" "Bioorg. Med. Chem." 28 115812 2020 https://doi.org/10.1016/j.bmc.2020.115812 ?SW???e "Synthesis of Hydrophilic Caged DAG-lactones for Chemical Biology Applications." "Takuya Kobayakawa, Hikaru Takano, Takahiro Ishii, Kohei Tsuji, Nami Ohashi, Wataru Nomura, Toshiaki Furuta & Hirokazu Tamamura*" "Org. Biomol. Chem." 18 4217-4223 2020 https://doi.org/10.1039/D0OB00807A ?SW???e "Cyclization Reaction-Based Turn-on Probe for Covalent Labeling of Target Proteins." "Hiroyuki Kojima, Yuki Fujita, Ryosuke Takeuchi, Yuka Ikebe, Nami Ohashi, Keiko Yamamoto & Toshimasa Itoh*" "Cell Chem. Biol. " 27 334-349 2020 https://doi.org/10.1016/j.chembiol.2020.01.006 ?SW???e "Endocannabinoid hydrolysis inhibition unmasks that unsaturated fatty acids induce a robust biosynthesis of 2-arachidonoylglycerol and its congeners in human myeloid leukocytes." "Caroline Turcotte, Anne Sophie Archambault, ?lizabeth Dumais, Cyril Martin, Marie Ren?e Blanchet, Elyse Bissonnette, Nami Ohashi, Keiko Yamamoto, Toshimasa Itoh, Michel Laviolette, Alain Veilleux, Louis Philippe Boulet, Vincenzo Di Marzo & Nicolas Flamand*" "FASEB J." 34 4253-4265 2020 10.1096/fj.201902916R ?SW???e "Soluble-type Small-molecule CD4 Mimics as HIV Entry Inhibitors." "Takuya Kobayakawa, Kiju Konno, Nami Ohashi, Kohei Takahashi, Ami Masuda, Kazuhisa Yoshimura, Shigeyoshi Harada* & Hirokazu Tamamura*" "Bioorg. Med. Chem. Lett." 29 719-723 2019 10.1016/j.bmcl.2019.01.011 ?SW???e "Flexibility of small molecular CD4 mimics as HIV entry inhibitors." "Takuya Kobayakawa#, Nami Ohashi# (# Equally contributed), Yuki Hirota, Kohei Takahashi, Yuko Yamada,Tetsuo Narumi, Kazuhisa Yoshimura, Shuzo Matsushita, Shigeyoshi HaradaN & Hirokazu Tamamura*" "Bioorg. Med. Chem." 26 5664-5671 2018 10.1016/j.bmc.2018.10.011 ?SW???e "Synthesis and Evaluation of Dimeric Derivatives of Diacylglycerol-Lactones as Protein Kinase C Ligands." "Nami Ohashi, Ryosuke Kobayashi, Wataru Nomura, Takuya Kobayakawa, Agnes Czikora, Brienna K Herold, Nancy E. Lewin, Peter M. Blumberg& Hirokazu Tamamura*" "Bioconjugate Chem." 28 2135-2144 2017 10.1021/acs.bioconjchem.7b00299 ?SW???e "Development of Anti-HIV Peptides Based on a Viral Capsid Protein." "Takaaki Mizuguchi, Nami Ohashi, Daichi Matsumoto, Chie Hashimoto, Wataru Nomura, Naoki Yamamoto, Tsutomu Murakami* & Hirokazu Tamamura*" "Biopolymers: Peptide Science" 108 e22920 2017 10.1002/bip.22920 ?SW???e "Small-Molecule CD4 Mimics Containing Mono-cyclohexyl Moieties as HIV Entry Inhibitors." "Nami Ohashi, Shigeyoshi Harada, Takaaki Mizuguchi, Yu Irahara, Yuko Yamada, Misato Kotani, Wataru Nomura, Shuzo Matsushita, Kazuhisa Yoshimura* & Hirokazu Tamamura*" "ChemMedChem a joint special issue with ChemBioChem: Protein Protein Interactions" 11 940-946 2016 10.1002/cmdc.201500590 ?SW???e "Evidence that ubiquitylated H2B corrals hDot1L on the nucleosomal surface to induce H3K79 methylation." "Linjiao Zhou, Matthew T. Holt, Nami Ohashi, Aishan Zhao, Manuel M. Muller, Boyuan Wang & Tom W. Muir *" "Nat. Commun." 7 10589 2016 10.1038/ncomms10589 ?SW???e "A minimally cytotoxic CD4 mimic as an HIV entry inhibitor." "Takaaki Mizuguchi, Shigeyoshi Harada, Tomoyuki Miura, Nami Ohashi, Tetsuo Narumi, Hiromi Mori, Yu Irahara, Yuko Yamada, Wataru Nomura, Shuzo Matsushita, Kazuhisa Yoshimura* & Tamamura Hirokazu*" "Bioorg. Med. Chem. Lett." 26 397-400 2016 10.1016/j.bmcl.2015.11.103 ?SW???e "Trivalent ligands for CXCR4 bearing polyproline linkers show specific recognition for cells with increased CXCR4 expression." "Wataru Nomura, Taisuke Koseki, Nami Ohashi, Takaaki Mizuguchia & Hirokazu Tamamura*" "Org. Biomol. Chem." 13 8734-8739 2015 10.1039/C5OB00891C ?SW???e "Anti-HIV Screening for Cell-penetrating Peptides Using Chloroquine and Identification of Anti-HIV Peptides Derived from Matrix Proteins." "Takaaki Mizuguchi, Nami Ohashi, Wataru Nomura, Mao Komoriya, Chie Hashimoto, Naoki Yamamoto, Tsutomu Murakami* & Hirokazu Tamamura*" "Bioorg. Med. Chem." 23 4423-4427 2015 10.1016/j.bmc.2015.06.020 ?SW???e "An In-cell Fluorogenic Tag-probe System for Protein Dynamics Imaging Enabled by Cell-Penetrating Peptides. " "Wataru Nomura, Nami Ohashi, Atsumi Mori & Hirokazu Tamamura*" "Bioconjugate Chem." 26 1080"1085 2015 10.1021/acs.bioconjchem.5b00131 ?SW???e "Screening for Protein Kinase C Ligands Using Fluorescence Resonance Energy Transfer." "Nami Ohashi, Wataru Nomura*, Natsuki Minato & Hirokazu Tamamura*" "Chem. Pharm. Bull. (Tokyo)." 62 1019-1025 2014 10.1248/cpb.c14-00419 ?SW???e "Isostere-based Design of 8-Azacoumarin-type Photolabile Protecting Groups: a Hydrophilicity-increasing Strategy for Coumarin-4-ylmethyls." "Tetsuo Narumi, Hikaru Takano, Nami Ohashi, Akinobu Suzuki, Toshiaki Furuta & Hirokazu Tamamura*" "Org. Lett." 16 1184-1187 2014 10.1021/ol5000583 ?SW???e "A CD4 mimic as an HIV entry inhibitor: Pharmacokinetics." "Chie Hashimoto, Tetsuo Narumi, Hiroyuki Otsuki, Yuki Hirota, Hiroshi Arai, Kazuhisa Yoshimura, Shigeyoshi Harada, Nami Ohashi, Wataru Nomura, Tomoyuki Miura, Tatsuhiko Igarashi, Shuzo Matsushita & Hirokazu Tamamura*" "Bioorg. Med. Chem." 21 7884-7889 2013 10.1016/j.bmc.2013.10.005 ?SW???e "Cell-Permeable Stapled Peptides Based on HIV-1 Integrase Inhibitors Derived from HIV-1 Gene Products." "Wataru Nomura, Haruo Aikawa, Nami Ohashi, Emiko Urano, Mathieu M?tifiot, Masayuki Fujino, Kasthuraiah Maddali, Taro Ozaki, Ami Nozue, Tetsuo Narumi, Chie Hashimoto, Tomohiro Tanaka, Yves Pommier, Naoki Yamamoto, Jun A. Komano, Tsutomu Murakami & Hirokazu Tamamura*" "ACS Chem. Biol." 8 " 2235 2244" 2013 10.1021/cb400495h ?SW???e "CD4 Mimics as HIV Entry Inhibitors: Lead Optimization Studies of the Aromatic Substituents." "Tetsuo Narumi, Hiroshi Arai, Kazuhisa Yoshimura, Shigeyoshi Harada, Yuki Hirota, Nami Ohashi, Chie Hashimoto, Wataru Nomura, Shuzo Matsushita & Hirokazu Tamamura*" "Bioorg. Med. Chem." 21 "2518-2526 " 2013 10.1016/j.bmc.2013.02.041 ?SW???e "Low-Molecular-Weight CXCR4 Ligands with Variable Spacers." "Tetsuo Narumi, Haruo Aikawa, Tomohiro Tanaka, Chie Hashimoto, Nami Ohashi, Wataru Nomura, Takuya Kobayakawa, Hikaru Takano, Yuki Hirota, Tsutomu Murakami, Naoki Yamamoto & Hirokazu Tamamura*" ChemMedChem " 8" 118-124 2013 10.1002/cmdc.201200390 ?SW???e "Fluorescent-Responsive Synthetic C1b Domains of Protein Kinase C as Reporters of Specific High-Affinity Ligand Binding." "Nami Ohashi, Wataru Nomura*, Tetsuo Narumi, Nancy E. Lewin, Kyoko Itotani, Peter M. Blumberg & Hirokazu Tamamura*" "Bioconjugate Chem." 22 82-87 2012 10.1021/bc100414a ?SW???e "Fluorescence-Quenching Screening of Protein Kinase C Ligands with an Environmentally Sensitive Fluorophore." "Wataru Nomura, Nami Ohashi, Yoshiaki Okuda, Tetsuo Narumi, Teikichi Ikura, Nobutoshi Ito & Hirokazu Tamamura*" "Bioconjugate Chem." 22 923-930 2011 10.1021/bc100567k ?SW???e "Synthetic Caged DAG-lactones for Photochemically Controlled Activation of Protein Kinase C." "Wataru Nomura, Tetsuo Narumi, Nami Ohashi, Yuki Serizawa, Nancy E. Lewin, Peter M. Blumberg, Toshiaki Furuta & Hirokazu Tamamura*" ChemBioChem 12 535-539 2011 10.1002/cbic.201000670 ?SW???e "Azamacrocyclic Metal Complexes as CXCR4 Antagonists." "Tomohiro Tanaka, Tetsuo Narumi*, Taro Ozaki, Akira Sohma, Nami Ohashi, Chie Hashimoto, Kyoko Itotani, Wataru Nomura, Tsutomu Murakami, Naoki Yamamoto & Hirokazu Tamamura*" ChemMedChem 6 834-839 2011 10.1002/cmdc.201000548 ?SW???e "CD4 Mimics Targeting the HIV Entry Mmechanism and Their Hybrid Molecules." "Tetsuo Narumi, Chihiro Ochiai, Kazuhisa Yoshimura, Shigeyoshi Harada, Tomohiro Tanaka, Wataru Nomura, Hiroshi Arai, Taro Ozaki, Nami Ohashi, Matsushita Shuzo & Hirakazu Tamamura*" "Bioorg. Med. Chem. Lett." 20 5853-5858 2010 10.1016/j.bmcl.2010.07.106 ?SW???e "Peptidic HIV Iintegrase Inhibitors Derived from HIV Gene Products: Structure-Activity Relationship Studies." "Shintaro Suzuki, Kasthuraiah Maddali, Chie Hashimoto, Emiko Urano, Nami Ohashi, Tomohiro Tanaka, Taro Ozaki, Hiroshi Arai, Hiroshi Tsutsumi, Tetsuo Narumi, Wataru Nomura, Naoki Yamamoto, Yves Pommier, Jun A. Komano & Hirokazu Tamamura*" "Bioorg. Med. Chem." 18 6771-6775 2010 10.1016/j.bmc.2010.07.050 ?SW???e "Development of Crosslink-Type Tag-Probe Pairs for Fluorescent Imaging of Proteins." "Wataru Nomura, Tomoaki Mino, Tetsuo Narumi, Nami Ohashi, Akemi Masuda, Chie Hashimoto, Hiroshi Tsutsumi & Hirokazu Tamamura*" "Biopolymers: Peptide Science" 94 843-852 2010 10.1002/bip.21444 ?SW???e "CD4 Mimics Targeting the Mechanism of HIV entry." "Yuko Yamada, Chihiro Ochiai, Kazuhisa Yoshimura, Tomohiro Tanaka, Nami Ohashi, Tetsuo Narumi, Wataru Nomura, Shigeyoshi Harada, Shuzo Matsushita & Hirokazu Tamamura*" "Bioorg. Med. Chem. Lett." 20 354-358 2010 10.1016/j.bmcl.2009.10.098 ?SW???e "Fluorogenically Active Leucine Zipper Peptides as New Tag-Probe Pairs for Protein Imaging in Living Cells." "Hiroshi Tsutsumi, Wataru Nomura, Seiichiro Abe, Tomoaki Mino, Akemi Masuda, Nami Ohashi, Tomohiro Tanaka, Kenji Ohba, Naoki Yamamoto, Kazunari Akiyoshi & Hirokazu Tamamura*" "Angew. Chem., Int. Ed." 48 9164-9166 2009 10.1002/anie.200903183 ?SW???e "Structure-activity Relationship Study on Artificial CXCR4 Ligands Possessing the Cyclic Pentapeptide Scaffold: The Exploration of Amino Acid Residues of Pentapeptides by Substitutions of Several Aromatic Amino Acids." "Tomohiro Tanaka, Wataru Nomura*, Tetsuo Narumi, Ai Esaka, Shinya Oishi, Nami Ohashi, Kyoko Itotani, Barry J. Evans, Zi-xuan Wang, Stephen C. Peiper, Nobutaka Fujii & Hirokazu Tamamura*" "Org. Biomol. Chem." 7 3805-3809 2009 10.1039/b908286g ?SW???e "Synthesis of Protein Kinase C? C1b Domain by Native Chemical Ligation Methodology and Characterization of Its Folding and Ligand Binding." "Nami Ohashi, Wataru Nomura*, Mai Kato, Tetsuo Narumi, Nancy E. Lewin, Peter M. Blumberg & Hirokazu Tamamura*" "J. Pept. Sci." 15 " 642-646" 2009 10.1002/psc.1161 ?SW???e "Structure-activity Relationship Study of CXCR4 Antagonists Bearing the Cyclic Pentapeptide Scaffold: Identification of the New Pharmacophore." "Tomohiro Tanaka, Hiroshi Tsutsumi*, Wataru Nomura, Yasuaki Tanabe, Nami Ohashi, Ai Esaka, Chihiro Ochiai, Jun Sato, Kyoko Itotani, Tsutomu Murakami, Kenji Ohba, Naoki Yamamoto, Nobutaka Fujii & Hirokazu Tamamura*" "Org. Biomol. Chem." 6 "4374-4377 " 2008 ?SW???e "Versatile Use of Acid-catalyzed Ring-opening of ?-Aziridinyl-?,?-enoates to Stereoselective Synthesis of Peptidomimetics." "Hirokazu Tamamura*, Tomohiro Tanaka, Hiroshi Tsutsumi, Koji Nemoto, Satoko Mizokami, Nami Ohashi, Shinya Oishi & Nobutaka Fujii*" Tetrahedron 63 9243-9254 2007 ?SW???e "Multimerized CHR-Derived Peptides as HIV-1 Fusion Inhibitors." "Wataru Nomura, Chie Hashimoto, Takaharu Suzuki, Nami Ohashi, Masayuki Fujino, Tsutoms" "Murakami, Naoki Yamamoto & Hirokazu Tamamura*" "Bioorg. Med. Chem." 21 " 4452-4458 " 2013 10.1016/j.bmc.2013.05.060