??.z%R ?0?0?0?0 W?? ?? T ?]?S ?0?0?0 ?QHrt^ DOI URL "[Original paper] " "Synthesis and Preclinical Evaluation of <sup>18</sup> F-Labeled Ketoprofen Methyl Esters for Cyclooxygenase-1 Imaging in Neuroinflammation" "Shukuri M, Mawatari A, Takatani S, Tahara T, Inoue M, Arakaki W, Ohno M, Doi H, Onoe H." "J Nucl Med." 63(11) 1761-1767 2022 10.2967/jnumed.121.263713. "[Original paper] " "Ex vivo imaging and analysis of ROS generation correlated with microglial activation in rat model with acute neuroinflammation induced by intrastriatal injection of LPS" "Shukuri M, Uchino M, Sakamaki T, Onoe S, Hosoi R, Todoroki K, Arano Y, Sakai T, Akizawa H, Inoue O." "Biochem Biophys Res Commun. " 584 101-106 2021 "doi: 10.1016/j.bbrc.2021.11.008." "[Original paper] " "Influence of Linker Molecules in Hexavalent RGD Peptides on Their Multivalent Interactions with Integrin ?v?3" "Mizuno Y, Kimura K, Onoe S, Shukuri M, Kuge Y, Akizawa H." "J Med Chem. " 64(21) 16008-16019 2021 10.1021/acs.jmedchem.1c01396. "[Original Paper]" "Evaluation of intracellular processes in quinolinic acid-induced brain damage by imaging reactive oxygen species generation and mitochondrial complex I activity" "Hosoi R, Fujii Y, Hiroyuki O, Shukuri M, Nishiyama S, Kanazawa M, Todoroki K, Arano Y, Sakai T, Tsukada H, Inoue O" "EJNMMI Res." 11(1) 99-108 2021 10.1186/s13550-021-00841-3 "[Original paper]" "A Simple Ex Vivo Semiquantitative Fluorescent Imaging Utilizing Planar Laser Scanner: Detection of Reactive Oxygen Species Generation in Mouse Brain and Kidney" "Hosoi R, Sato S, Shukuri M, Fujii Y, Todoroki K, Arano Y, Sakai T, Inoue O." "Mol Imaging. " 18 1536012118820421 2019 10.1177/1536012118820421 "[Original paper] " "Unexpected decrease in in vivo binding of [<sup>3</sup>H]QNB in the mouse cerebral cortex in the developing brain - A comparison with [<sup>11</sup>C]NMPB" "Inoue O, Sato T, Kobayashi K, Gee A, Shukuri M, Zhang MR." "Nucl Med Biol. " 67 15-20 2018 " 10.1016/j.nucmedbio.2018.10.004" "[Original paper]" "Detection of Cyclooxygenase-1 in Activated Microglia During Amyloid Plaque Progression: PET Studies in Alzheimer's Disease Model Mice." "Shukuri M, Mawatari A, Ohno M, Suzuki M, Doi H, Watanabe Y, Onoe H." "J Nucl Med." 57 291-296 2016 "[Original paper]" "Exploratory human PET study of the effectiveness of <sup>11</sup>C-ketoprofen methyl ester, a potential biomarker of neuroinflammatory processes in Alzheimer's disease." "Ohnishi A, Senda M, Yamane T, Mikami T, Nishida H, Nishio T, Akamatsu G, Ikari Y, Kimoto S, Aita K, Sasaki M, Shinkawa H, Yamamoto Y, Shukuri M, Mawatari A, Doi H, Watanabe Y, Onoe H." "Nucl Med Biol. " 43 438-444 2016 [Review] "^yL}?p?uk0J0Q0?0?0?0?0?0?0?0?0?0?0?0n0PETRP[?0?0?0?0?0?0 (AYUMI ?p?uh0^yL} Y'`)" "?[?EQBz, >\ Nim??" ;Sf[n0B0?00 248 907-911 2014 [Review] ";N??PET?e-?9}?N ?V?z?|^y?0^yL};SBvxvz?0?0?0?03??uKaq}T?0?0N?0?0?0?0?0?0?0k0J0Q0?0PET?0?0?0?0?0?0xvzn0?S?0D}0" "?R?][N, ?[?EQBz, *Y0u?m?y, ?N?g?`P[, ?h N?ON, *jq\?m, ???]??, ,g0uf[, ~g0uZS?S" "PET journal??" 25 4-6 2014 "[Original paper]" "Human whole-body biodistribution and dosimetry of a new PET tracer, [<sup>11</sup>C]ketoprofen methyl ester, for imagings of neuroinflammation." "Ohnishi A, Senda M, Yamane T, Sasaki M, Mikami T, Nishio T, Ikari Y, Nishida H, Shukuri M, Takashima T, Mawatari A, Doi H, Watanabe Y, Onoe H." "Nucl Med Biol." 41 594-599 2014 [Review] "?0?0?0?0?0?0?0?un0:??eh0?lBvn0gHQ?z: ?0?0?0?0?0?0?0?un0?lBv??0?0?0?0?0?0?0dRh0W0f0n0NSAIDsn0?S??'`" "?[?EQBz, >\ Nim??" "PET journal " 21 10-12 2013 [Review] "z?OP[9e Y?0?0?0n03?_j??RP[?0?0?0?0?0?0 (yr? RP[?0?0?0?0?0?0?yf[n0gHQ?z)" "4l???^, ?[?EQBz, >\ Nim??" "0}? " 45 59-62 2013 "[Original paper]" "Assessment of radioligands for PET imaging of cyclooxygenase-2 in an ischemic neuronal injury model." "Ji B, Kumata K, Onoe H, Kaneko H, Zhang MR, Seki C, Ono M, Shukuri M, Tokunaga M, Minamihisamatsu T, Suhara T, Higuchi M." "Brain Res. " 1533 152-162 2013 "[Original paper]" "The food reaching test: a sensitive test of behavioral improvements by deep brain stimulation in MPTP-treated monkey." "Asakawa T, Sugiyama K, Akamine S, Yokoyama C, Shukuri M, Mizuma H, Tsukada H, Onoe H, Namba H." "Neurosci Res." 74 122-128 2012 [Review] "?uKa?yf[n0_0?0n0PET?0?0?0?0n0??zvh0z?OP[9e Y?0?0?0?0?0?0?0(uD0_0uSORP[?0?0?0?0?0?0 (yr? RP[?0?0?0?0?0?0n0gHQ?z) " "?[?EQBz, 4l???^, >\ Nim??" g?e;Sf[ 66 2354-2360 2011 [Review] "<sup>11</sup>CjX?^??0?0?0?0?0'`?b?p?u??(NSAIDs)k0?0?03??p?un0?0?0?0?0?0?0 (yr? RP[?0?0?0?0?0?0n0gHQ?z)" "?[?EQBz, ??\}YV?, >\ Nim??" "PET journal " 15 28-30 2011 "[Original paper]" "In vivo expression of cyclooxygenase-1 in activated microglia and macrophages during neuroinflammation visualized by PET with <sup>11</sup>C-ketoprofen methyl ester." "Shukuri M, Takashima-Hirano M, Tokuda K, Takashima T, Matsumura K, Inoue O, Doi H, Suzuki M, Watanabe Y, Onoe H." "J Nucl Med." 52 1094-1101 2011